As of the date of this review, 37 monoclonal antibody products are approved for use in cancer treatments in the United Kingdom. Currently, the antibody therapeutics market is dominated by monoclonal immunoglobulins (IgGs). New types of recombinant antibody therapeutics developed more recently include bispecific recombinant antibodies and other recombinantly produced functional proteins. This review focuses […]

Viruses have been used as possible agents to treat cancer for more than a century.9 With the development of cloning technology, a variety of viruses could be genetically engineered to selectively infect and lyse tumor cells. The increased understanding of viral mechanisms of action, including activating innate and adaptive antitumor immunity and modulating the TME, […]

Abstract Phagocytosis, a vital defense mechanism, involves the recognition and elimination of foreign substances by cells. Phagocytes, such as neutrophils and macrophages, rapidly respond to invaders; macrophages are especially important in later stages of the immune response. They detect “find me” signals to locate apoptotic cells and migrate toward them. Apoptotic cells then send “eat […]

In approximately 15-20% of the patients diagnosed with breast cancer, it comprises the triple negative (TN) subtype, which until recently lacked targets for specific treatments and is known for its aggressive clinical behavior in patients with metastatic disease. TNBC is considered the most immunogenic breast cancer subtype due to higher levels of tumor infiltrating lymphocytes […]

  Thank you for your support and contribution. This enables us to educate the public about  Biological Therapies for cancer treatment. The information on this website is the most current research being offered in our best medical school’s clinical trials.